The couple, who met while co-starring on the ABC soap opera All My Children, tied the knot in 1996, and share three children -- Michael, 18, Lola, 14, and Joaquin, 13.
The special anniversary comes amid controversy surrounding Ripa's temporary leave from her daytime talk show Live! With Kelly and Michael, after news broke that he co-host, Michael Strahan, would be departing the show for a spot on Good Morning America.
Ripa and Consuelos took a celebratory trip that was overshadowed by the drama on the show, but it appeared the two made the best of the situation. Ripa was all smiles while the couple headed to their vacation in Turks and Caicos on April 21. Ripa returned to the show the next week.
Ripa and Strahan won a Daytime Emmy on Thursday for Best Entertainment Talk Show Host for their co-hosting duties on Live! with Kelly and Michael. Neither were at the ceremony, so Dr. Oz -- who nabbed the Outstanding Informative Talk Show Host award -- accepted the gold statue on their behalf.