Jennifer Aniston's mother, Nancy Dow, died on Wednesday at the age of 79.
The Friends star and her half-brother, John Melick, confirmed the news, sharing that their mother "passed peacefully, surrounded by family and and friends after enduring a long illness," in a statement released to ET.
"We ask that our family’s privacy be respected as we grieve our loss," they continued.
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Dow had been in poor health since 2011, when she suffered a stroke, followed by another the next year, People reports. The former actress was married to Aniston's father, soap opera star John Aniston, from 1965 to 1980. She was previously married to Melick's father, Jack Melick, from 1956 to 1961.
In January 2015, Aniston opened up about her formerly-strained relationship with her mother in an interview with The Hollywood Reporter, revealing that she and Dow didn’t speak for several years, describing her mother as being "very critical" when Aniston was young.
However, the two had reconnected in recent years and Aniston said at the time that her relationship with Dow was "all fine."
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Like Aniston and her father, Dow was a performer who appeared in a number of television series back in the 1960s, including The Beverly Hillbillies and The Wild Wild West.
Recently, fellow movie star Johnny Depp also lost his mother, Betty Sue Palmer, who died on Friday after a long illness at the age of 81. Watch the video below for more.