Sarah Silverman has a bone to pick with Marco Rubio.
The 45-year-old comedian tweeted a jab at the senator, also 45, over his recent comments about the Zika virus.
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"I don't like name calling and I'm trying to stay open but that's a real sexist & c**ty move @marcorubio," she wrote on Saturday.
The I Smile Back star was responding to Rubio's recent statements that he doesn't believe pregnant women infected with the Zika virus should have the right to an abortion, even if the child might be born with severe microcephaly.
"I understand a lot of people disagree with my view -- but I believe that all human life is worthy of protection of our laws," the senator told Politico. "And when you present it in the context of Zika or any prenatal condition, it's a difficult question and a hard one."
"But if I'm going to err, I'm going to err on the side of life," he added.
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Rubio's statements are particularly relevant after Congress failed to pass a Zika-relief bill in June. The virus has spread quickly throughout the senator's state of Florida, where 422 cases have been diagnosed so far, more than any other state in the nation.
Another celebrity has recently entered herself into the Zika conversation as well: Hope Solo.
Last month, the soccer pro snapped a selfie while wearing a mosquito net and holding a huge bottle of insect repellant. "Not sharing this!!! Get your own! #zikaproo #RoadtoRio," she captioned the shot.
That controversial post led to her getting booed by the crowd at the 2016 Rio Olympics.
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While the goalkeeper refuses to back down from her statements, she did offer an explanation for the controversial posts, telling Sports Illustrated on Thursday that she wants to "start a family." "I did know they were booing, but it doesn't affect me," she explained. "I wish people understood that I did my due diligence before coming to Brazil."
See more in the video below.