The 46-year-old actress posted an amazing Instagram video of herself dancing to DJ Khaled and Drake's hit "For Free" on Instagram on Wednesday, breaking it down with music producer Norm Thump Nixon and her Grey's Anatomy co-star, Debbie Allen.
Pompeo looks adorable going makeup-free in the video and throwing her hair in a ponytail, as she lets loose during downtime from her hit ABC show.
Season 13 of Grey's Anatomy premieres Thursday, Sept. 22, at 9 p.m. ET/PT on ABC.
The mother of two recently spoke about her longtime television gig, and admitted she had to let go of her "ego" to stay on the show. Pompeo has played Dr. Meredith Grey since the show's 2005 debut, and according to Forbes, is the fourth highest-earning TV actress, earning a whopping $14.5 million this year.
"I have to go out into the landscape and try to get jobs, and deal with, you know, 'Am I good enough? Am I pretty enough? Am I smart enough? Am I talented enough? Am I young enough?'" Pompeo said during her appearance on Good Morning America earlier this month.
"You really have to, sort, of, delineate your ego from everything," she continued. "Your ego is what would drive you to say, 'Oh this isn't cool. I need to go be a movie star or do something else.' But your ego really is your biggest enemy."