David Arquette and Wife Christina Expecting Baby No. 2!

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David Arquette is going to be a dad again.

David Arquette is about to become a father of three.

The 45-year-old actor and his wife, Christina Arquette, announced on Wednesday that the couple is expecting their second child together -- a baby boy. The two are already parents to their son, 2-year-old Charlie West, whom they welcomed in April 2014. David also has a 12-year-old daughter, Coco, with his ex-wife, Courteney Cox.

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David posted an adorable video of Charlie kissing his wife's sonogram on Instagram while saying, "Hi, baby."

"So incredibly blessed and honored that my wife @christinaarquette is pregnant with a baby boy!" he captioned the sweet post. "Thank you Christina and humbled gratitude to G-D for this tremendous gift! Charlie and Coco are so excited and I am over the moon!!!"

David and 35-year-old Christina -- a former Entertainment Tonight correspondent -- have been married since last April.

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The news is presumably a bit bittersweet for the Scream actor, as his sister, actress and transgender advocate Alexis Arquette, died last month after battling HIV for 29 years. She was 47 years old.

"Thank you all for your love and kind words about Alexis," David tweeted about the heartbreaking news. "My hero for eternity."

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