EXCLUSIVE: Lisa Vanderpump Reacts to Mike and Scheana Shay's Divorce: 'It's Quite Disheartening'

Plus, the reality star teases what's to come on season seven of 'The Real Housewives of Beverly Hills.'

Lisa Vanderpump is feeling "the ripple effects" of a "disheartening" breakup.

ET caught up with the 56-year-old reality star at The Real Housewives of Beverly Hills premiere at the Sofitel Hotel in Beverly Hills, California, on Friday, where she opened up about Mike and Scheana Shay's recent divorce filing.

WATCH: Camille Grammer Confirms 'Real Housewives of Beverly Hills' Return: Our Show 'Never Lacks the Drama'

The Vanderpump Rules stars filed the dissolution of marriage petition in Los Angeles on Tuesday, listing the date of separation as Nov. 9. Both said in a statement, however, that they had "come to an amicable decision on all matters."

"Well, you're going to see some of [what went wrong] on the end of the season," Lisa told ET's Brice Sander. "I'm very protective of Scheana, and with what went down last year -- you know, what she talked about [with Mike's] addiction -- I felt really quite incensed because I have a lot of sympathy for people with addiction."

As fans of the popular Bravo series may recall, Scheana confronted Mike about his drug addiction issues last season.

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"I was a little upset with the fact they entered into this marriage without [Scheana] being aware of what she was taking on," Lisa continued. "Scheana's a great girl, she really is, and to see this fairytale come to an end, it was quite disheartening, really. They are young and they're growing up, but these -- I call them kids, but they're not really -- they're late 20s, some early 30s."

"What is so extraordinary," she added, "is the fact that the cohesion between this group and the authenticity is why we created this show … because they've known each other long. So, you see the splinter effects, the ripple effects, the ramifications of what's going on."

As for the "refreshing" new season of The Real Housewives of Beverly Hills, which returns to Bravo on Tuesday, Dec. 6 at 9 p.m. ET, Lisa is excited to make her comeback, and for fans to finally meet her friend (and RHOBH newbie!) Dorit Kemsley.

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"The shows afforded me some incredible opportunities and I really can't minimize that, but sometimes it gets very difficult and it was very difficult last year," she admitted. "I had a lot of tears, and I thought, '[I] just can't do this anymore.'"

"But no, I have my new friend Dorit, who I think you're going to love," Lisa continued. "She gets herself in a little bit of trouble. She's the newbie, but it did get a little bit heated again. I mean, it always does -- I think it's the whole premise of putting six women together and trips and this and that and the only premise of reality television is to always speak your truth, so there ya go!"

The network released the all-new opening sequence for season seven of the series on Friday, which featured the housewives' new taglines, Lisa's being, "The crown is heavy, darlings. So just leave it where it belongs."

"I tried to have fun on the show, and I think that's what the show should primarily be about, so I always like my taglines to reflect how I'm feeling," Lisa explained to ET. "And it was just like, 'OK, you beat me up last year, now back off,' you know? I think last year was funny. I'm passionate about dogs, not crazy about bitches, so I always like to kind of write my own."

WATCH: Mike and Scheana Shay File for Divorce: 'Our Story Will Continue on Through Love'