Jimmy Kimmel Breaks Down in Tears Over Son's Birth and Successful Open-Heart Surgery in Emotional Monologue

Jimmy Kimmel gave an emotional monologue on Monday's Jimmy Kimmel Live.

The 49-year-old got personal while opening the show, revealing that his wife, Molly McNearney, had given birth to their son, William "Billy" Kimmel -- and then the comedian broke down in tears as he revealed the newborn's heart disease and subsequent successful surgery.

WATCH: Jimmy Kimmel and Wife Molly McNearney Expecting Baby No. 2

A few hours Kimmel's son was born on April 21, a nurse noticed he was "purple" and doctors diagnosed him with a heart defect. At three days old, Billy had open heart surgery at Children's Hospital Los Angeles.

"Six days after open heart surgery, we got to bring him home, which was amazing," said Kimmel, revealing that Billy will have to have two more procedures on his heart later in life. "He's doing great. He's eating, he's sleeping. He peed on his mother today while she was changing his diaper. He's doing all the things that he's supposed to do."

The father of four, who also shares 2-year-old daughter, Jane, with McNearney, began to cheer up as he shared photos of his newborn.

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"You can see Jane's pretty excited about having another kid in the house," he joked while displaying a sweet family picture.

"This is me in a coma," he described alongside another photo of him holding Billy.

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"It was an enormous team effort," Kimmel shared, thanking the doctors, nurses and staff at Cedars Sinai Medical Center and Children's Hospital Los Angeles, and encouraging viewers to donate to CHLA.

Watch Kimmel's moving monologue below:

Kimmel will spend the rest of the week on paternity leave, while friends like Will Arnett and Kristen Bell fill in. See the schedule below:

Tuesday: Host Will Arnett, with guests Maya Rudolph and Ben McKenzie and musical guest Incubus

Wednesday: Host Anthony Anderson, with guest George Lopez and musical guest Future

Thursday: Host Kristen Bell, with guests Charlie Hunnam and Adam Scott and musical guest Alison Krauss

Friday: Host David Spade, with guest Guy Ritchie and musical guest alt-J

Kimmel took to Twitter after the show to thank fans for their "loving tweets about our son Billy and for your donations."

WATCH: Jimmy Kimmel and Molly McNearney's Daughter Jane Does an Adorable 'Impression' of Her Pregnant Mom

Jimmy Kimmel's 2-Year-Old Daughter Does Hilarious Impression of Her Pregnant Mom!

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