According toPage Six, who first reported the news, Macpherson has already moved out of their Miami home.
Macpherson's marriage to Soffer was her second. She was previously married to photographer Gilles Bensimon, though they called it quits in 1989 after three years together. She also has two sons from her relationship with French financier Arpad Busson.
It appears Macpherson is keeping busy focusing on her children. Last week, she Instagrammed a recent photo of her youngest son, Aurelius, graduating from middle school.
"Same @tomford Gucci suit I wore to his christening 2005," Macpherson wrote.