Christina Applegate Quits 'Up All Night'

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Due to creative differences, Up All Night star Christina Applegate has announced her plans to leave the NBC sitcom.

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"It's been a great experience working on Up All Night, but the show has taken a different creative direction and I decided it was best for me to move on to other endeavors," Applegate tells Deadline. "Working with Lorne Michaels has been a dream come true and I am grateful he brought me into his TV family. I will miss the cast, producers and crew, and wish them the best always."

Applegate's departure is believed to be linked to the show's plans to switch from single-camera to multi-cam filming format and begin taping in front of a live studio audience.

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Up All Night, also starring Maya Rudolph and Will Arnett, just wrapped its second season.