'Big Bang Theory' Cast Rocks 'Rocky Horror'

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The cast of The Big Bang Theory donned their best fishnets, feather boas and eyeliner Wednesday night for a hilarious one-time performance of The Time Warp from The Rocky Horror Picture Show, all for a very special cause, and we've got the highlights!

Pics: Two Looks, One Star

"This is the fifth year we, as The Big Bang cast, have come here to do a number to keep bringing attention to this cause," said Jim Parsons at the 21st Annual "A Night at Sardi's" to benefit the Alzheimer's Association at the Beverly Hilton Hotel in Los Angeles. "There is no cure yet and it's just very important to keep attention on it until there is one."

He added before the performance, "None of us sing very well, and it's never necessarily good what we do, but like a train wreck you can't take your eyes off it, so there's the attention."
Dressed up like Tim Curry's Dr. Frank N. Furter, Jim was joined onstage by co-stars Kaley Cuoco, Johnny Galecki , Simon Helberg, Melissa Rauch, Mayim Bialik and Kunal Nayyar.

Video: Is 'Big Bang Theory' Cast Like Their Characters?

Other performers belting out the Best of Broadway Wednesday night included Emmy Rossum, Jason Alexander, Zachary Levi and Steven Weber. The charity event was hosted by Jason Bateman and Ron Howard was on hand to present the Abe Burrows Entertainment Award to longtime friend and collaborator Brian Grazer. Since the inception of the event, "A Night at Sardi's" has raised more than $21 million to support the Alzheimer's Association mission.

CLICK HERE for more info on the Alzheimer's Association.