EXCLUSIVE: Jeffrey Dean Morgan Has a Heartbreaking 'Grey's Anatomy' Moment on 'Extant'

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The tables have turned for Jeffrey Dean Morgan.

On this week’s all-new episode of Extant, Morgan’s character J.D. Richter finds himself in a bind when Halle Berry’s Molly Woods is infected with a deadly virus, leaving her in a coma.

WATCH: Halle Berry Wakes Up Next to a Naked Stranger in Bed on 'Extant'

In the heartbreaking hospital scene, which ETonline exclusively debuts, an emotional J.D. pleads with Molly to wake up and not give up. It’s a moment that’s familiar to Morgan, whose Grey’s Anatomy character Denny Duqette (R.I.P.!) experienced a similarly emotional speech from Dr. Izzie Stevens (Katherine Heigl). (Relive the Kleenex-worthy moment here!)

“You’ve turned my world upside down and then you gave it a good shake. But you know what, I wouldn’t change a second of it,” J.D. tells a comatose Molly.

“You opened my eyes, Molly. You made me see things in myself and other people that I never would have found on my own. That’s what you do – you make the world see things. That’s your gift. You are the bravest and strongest person that I’ve ever met in my entire life,” he continues to plead.

WATCH: Halle Berry and Jeffrey Dean Morgan Dish on Exciting 'Extant' Season 2

And sometimes it takes a near-death situation to bring a person’s true feelings out, as in the case here. If there was any doubt about J.D.’s feelings toward Molly, this speech may have sealed it once and for all.

“People – they need you … I need you,” he says, clearly distraught.

Will Molly be the same again if or when she wakes up?

airs Wednesdays at 9 p.m. ET/PT on CBS.

Halle Berry and Jeffrey Dean Morgan spoke to ET about bringing the sexiness to CBS’ Extant! Find out why season two is a must-watch!