EXCLUSIVE: Rob Lowe Is a Quick Study on the Set of 'Code Black': 'This Is Medical Boot Camp'

This video is unavailable because we were unable to load a message from our sponsors.

If you are using ad-blocking software, please disable it and reload the page.

It takes more than just a handsome face to make it in the O.R., which Rob Lowe quickly found out on the set of Code Black.

"This is medical boot camp," Lowe told ET. "The hardest thing is getting the gloves on."

PICS: Rob Lowe Scrubs in For His First Day on 'Code Black'

The West Wing alum dons scrubs alongside co-stars Marcia Gay Harden and Luis Guzman for the CBS medical drama, which he has joined in its second season.

"It's a battle of looking good and looking like you know what you're doing," Lowe told Harden.

"It's not a battle for you," Harden replied without hesitation. "It's not a battle for Rob Lowe."

"I'm learning from the master," Lowe insisted. "I'm following everything that you do."

Harden revealed that Lowe was a quick study.

"Rob is already the master," she said. "This is what he knows: everything interesting you do, you do near your face. You snap your gloves in your face."

MORE: Get the Details on Rob Lowe's Aggressive 'Code Black' Character!

This isn't Lowe's first time playing a doctor. He had an unforgettable turn as Liberace's plastic surgeon in Behind the Candelabra, but he's largely stayed away from the tools of the trade.

"I've spent most of my career trying to avoid acting with props," Lowe admitted. "No longer."

Code Black's season two premiere is set to air Wednesday, Sept. 28 on CBS.