Jennifer Aniston and Reese Witherspoon Are Set to Co-Star in a TV Series About Morning Shows

The power pairing would mark Aniston's first major return to the small screen since 'Friends.'

Jennifer Aniston and Reese Witherspoon are poised to be a TV power pair!

The two actresses are set to co-star in a new series about TV morning shows, which will soon be shopped around to premium cable networks and streaming services, ET can confirm.

The Hollywood Reporter first broke the story.

WATCH: Jennifer Aniston Reveals Why She's Considering a Return to TV

Former HBO head of drama Michael Ellenberg is leading production, while Jay Carson (House of Cards) is signed on for the script.

This is something of a dream casting for Friends fans, who will recall that Witherspoon played Aniston's little sister on the beloved comedy series, way back in the day.

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Can't wait to see these "sisters" back together again!

While both stars are well known to be big screen powerhouses, Witherspoon recently found her "golden age of TV" success with the critically-acclaimed HBO mini-series (that may not be so "mini" after all), Big Little Lies, and Aniston has expressed recent interest in making a small screen comeback.

"I’ve thought about [returning to TV] a a lot. That’s where the work is," Aniston told Variety in January. "That’s where the quality is. At this point in my career, I want to be part of wonderful stories, exciting characters, and also just having a good time."

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Well, this sounds like one great story we can't wait to see!

Watch the video below for more of Aniston's comments on returning to television.