Larson, whose nuanced performance in the emotionally charged drama, Room, has received universal acclaim, gave a heartfelt and earnest acceptance speech, thanking everyone involved with the success of the film, including the moviegoers.
She made sure to give a special thanks to her adorable 9-year-old co-star, Jacob Tremblay, for being her "partner through this in every way possible."
Larson has been cleaning up this awards season, taking home the top prize at the SAG Awards, the BAFTAs and the Golden Globes.
In fact, Larson almost missed her Golden Globes win after taking a bathroom break. The actress recounted the hilarious near-mishap to ET in January, explaining, "All I remember is I needed to go to the bathroom."
"I went to the bathroom and as I was leaving, Helen Mirren was like, 'Don't go right now. Your category is coming up.' And I said, 'No it's not. I've got like an hour to go.' Then Kate Winslet was like, 'Don't go right now.' I said, 'I have to. I still have an hour.' I wasn't looking at the clock, which was a big problem."