From their first meeting on the set of 'Tropic Thunder' to their top secret wedding in 2015, the couple's story seemed to be headed for a happy ending.
ET revisits all the great things the couple has previously told us over the past few years.
The couple may have split, but they still have much love for each other.
ET breaks down the last few times we've seen the now-estranged couple out and about.
They divorced in 2005, and a source tells ET the two still keep in touch, but that's really all it is.
The newly single actress is staying busy after ending her two and a half year marriage.
The actress was photographed arriving to a film studio in Los Angeles on Thursday.
After announcing their separation on Thursday, ET has learned more about what's behind the split.
A source tells ET that the unexpected breakup was actually a long time coming.
On Wednesday, the couple announced their separation after two and a half years of marriage.
ET is diving into the couple's lengthy love story and examining how their relationship unfolded in and out of the public eye.
In a statement released on Thursday, Aniston and Theroux announced that the decision to separate 'was made mutually and lovingly at the end of last year.'
The pair announced their separation in a statement to ET on Thursday.
The couple announced their breakup on Thursday.