Dr. Mehmet Oz and Dr. Sanjay Gupta will also be taking their place behind the host's lectern later this season.
As part of their appearances, a donation will be made to a charity of their choice.
'Not many things in life are perfect, but Alex did this job pretty much perfectly for more than 36 years,' the former contestant raved.
The legendary TV host said 'So long!' one last time on Friday.
In the show's premiere, 'The Chase' honored the late game show icon.
Plus, Ken Jennings talks about the possibility of becoming the new host of 'Jeopardy!'
ET spoke with 'The Chase' stars Ken Jennings, James Holzhauer, Brad Rutter, and host Sara Haines ahead of its premiere Jan. 7 on ABC.
The game show winner will soon be temporarily hosting 'Jeopardy!' following the passing of Alex Trebek.
'I want to win this for Alex, but taking down Meryl Streep (& Full Cast) is gonna be sweet.'
