ET's Lauren Zima caught up with the 50-year-old actress at the Los Angeles premiere of Downsizing, and noted that Jeff Goldblum had confirmed that he would be reprising his role as Malcolm in the film franchise -- so does that mean Dern may also be making a cameo?
"[It] could be fun," she teased. "I mean, I love Ellie Sattler."
Further praising her character from the 1993 movie, Dern added, "She's a tough feminist, come on! We need her back."
The Emmy winner is also expected to reprise her role as Renata Klein when HBO's Big Little Lies miniseries returns for a second season, but admits that she doesn't know for certain if her character will be coming back.
"I don't know if I'm confirmed but I know we all want to be there," she said. "I'm sure we have a deep plan about that."
Dern won her first Emmy for her role in the miniseries and is currently nominated for a Golden Globe. When asked what it was like to see Big Little Lies get so much recognition, she mused, "Just gorgeous and I think it speaks to the kind of storytelling people want to see."
She even recalled a play date she had with her Big Little Lies co-star, Reese Witherspoon, where they ran into some unsuspecting fans of the show. "Reese and I took our kids to an amusement park and a bunch of frat boys came up to us -- in their early 20's on Spring Break -- and they were like, 'Oh my god, Big Little Lies is our favorite show,'" she remembered. "There's a lot of different audiences interested in storytelling that happens to be female characters."
In the meantime, Dern stars in Downsizing, which hits theaters on Dec. 22. Check out more of what she had to say about Big Little Lies: