The 'Taken' star appeared on 'Watch What Happens Live With Andy Cohen.'
In November, a report claimed that the 65-year-old Irish star had met Markle at a Hillary Irish fundraiser in New York City and a photo even surfaced that was purportedly of the two actors posing together.
However, on Thursday's episode of Watch What Happens Live With Andy Cohen, Neeson insisted, "I never met Meghan Markle."
The Taken star added that he's also never been introduced to Harry either, but he has met his father, Prince Charles, "a couple of times." Neeson said he was most impressed with Charles' wife, Camilla, Duchess of Cornwall, because she showed up to an event at Buckingham Palace "with a cigarette and a glass of red wine."
Further recalling Camilla's grand entrance, Neeson added, "I thought, 'I like you.'"
Taraji P. Henson was also on WWHL, and quipped, "We would have been BFFs from that moment on."
Neeson's ex-girlfriend, Helen Mirren, has met Harry and gushed over him and his brother, Prince William, while on The Ellen DeGeneres Show on Thursday. "They're both unbelievably charming, very straightforward, very charming, and a great credit to their father, [Prince Charles]," she said in praise of the princes.
Mirren also noted that while she does know Harry, she will not be attending his wedding in May.