EXCLUSIVE: Tom Hanks Is Out to Save All of Mankind in 'Da Vinci Code' Sequel 'Inferno'

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Tom Hanks takes on his toughest challenge yet as Robert Langdon on the set of Inferno.

"It's people in pain and there's a lot of blood and there's a lot of fire and there's sinners and there's a lot of anguish," Hanks says in a behind-the-scenes clip.

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The Oscar winner reprises his role as the beloved character for the third installment of Dan Brown's The Da Vinci Code franchise. The original movie and its sequel, Angels & Demons, have made upwards of $1.2 billion combined, but what makes this one different is that Langdon has no answers.

In the new film, the professor of religious iconology teams up with Dr. Sienna Brooks (Felicity Jones) to race across Europe and foil a deadly global plot, all the while struggling to remember anything about his past.

"Hell for Langdon in this movie is very much a state of mind," Hanks says. "He's tortured by the fact that he's ignorant of the origins of why he's there."

In attempting to stop a killer virus from wiping out much of mankind, Langdon must search for clues hidden in Sandro Botticelli's classic painting of Dante's Inferno.

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"Let's call it a ticking time bomb," Hanks explains. "And he has to find this bag with a horrible substance inside it before it goes off."

Inferno is set to hit theaters Oct. 28.