Stars of music, film and television (plus an Olympic champion or two) pooled their collective resources and manned the phones at the 2012 Stand Up To Cancer telecast in Los Angeles on Friday.
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Gwyneth Paltrow, Tim McGraw, Gabrielle Douglas and Stacy Keibler were just a few of the celebrities who gussied down in support for the cause by donning SU2C tees at the red carpet event.
Paltrow, who lost her father (director-producer Bruce Paltrow) to cancer a decade ago, served as executive producer to the broadcast, telling ET the opportunity was an "honor."
"It's been an incredible honor to produce it and to really be involved in the production and to have my ideas incorporated. It's been wonderful-- It's been challenging in a wonderful, positive way."
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Joining her on the carpet was Paltrow's Country Strong co-star Tim McGraw, who shares a similar, tragic loss with the actress.
"My dad died of cancer and my mother had cancer when I was young," said McGraw, adding that sadly, the list of friends and family members he's known with the disease goes on and on.
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"It's an issue that everybody deals with in one way or another with family; with friends-- It touches everybody."
Want to learn how you can stand up to cancer? Visit the SU2C website here for more.