The Hangover stardoesn't waste time ribbing Seinfeld to his face, insulting him while stage-whispering to someone off-camera.
"I had the president and Hillary Clinton on last, and now I have this guy," he gripes. "It's like 'I love the '90s.' Might as well have Lorena Bobbitt as a guest, you know? ... Find a legitimate guest!"
"Do you think if they only made one Hangover and didn't make the other two, it would be considered a comedy classic?" he asks. "Do you think that you destroyed what would have been a comedy classic by the cash grab of two and three?"
Later, Cardi B makes a surprise appearance, and Galifianakis totally ignores Seinfeld and relegates him to sitting on a milk crate. The "Be Careful" rapper also hilariously shades the comedian when he goes in for a hug, causing Seinfeld to quip, "This is the opposite of what happened with Kesha."