The 'Late Night' host found some laughs while acknowledging the Time's Up movement in an opening bit free of the typical song and dance.
The comedians tweeted their support for Meyers ahead of the big night.
Get all the details on the 75th Golden Globe Awards
The 63-year-old media mogul will receive the honor at the 75th Annual Golden Globe Awards on Sunday.
ET caught up with Meyers as he helped unroll the red carpet on Thursday.
A source tells ET who will likely fill the newsman's NBC gig as 'Late Night' host Seth Meyers slams his former network colleague.
The 'Late Night' host had lots of jokes about the reported button under the desk of the former 'Today' show host.
The former 'Today' show anchor's surprising firing was the topic of many hosts' monologues on Wednesday night.
The couple are already parents to 1-year-old son Ashe.
The 'Late Night' star has signed on to emcee the star studded awards show in January, taking the reins from last year's host, Jimmy Fallon.
Fallon and his fellow late night talk show hosts somberly reflected on the horrific shootings.
The 'Mother' star stopped by 'Late Night With Seth Meyers' on Thursday
The former president's message of hope, love and tolerance resonated with a lot of people around the world.
Jimmy Fallon, Seth Meyers and Jimmy Kimmel reflected on the tragic terror attack during their respective late night shows on Monday.