"[Becoming a zombie] becomes an awakening for [Sheila's] life, and that gave me one too," the 41-year-old Golden Globe winner told ET's Cameron Mathison at the premiere of her new Netflix series on Wednesday. "I lost like, 20 pounds playing her and had an attitudinal shift and plucked my eyebrows and, I don’t know, just started thinking like a woman again. And it was amazing."
Barrymore said that she began to fall in love with her unique character during production, and would ask herself "'What would Sheila do?'"
"She's got this great feminist empowerment thing going for her that I think was very positive for me," Barrymore added, joking, "in a very sick and wrong way."
Barrymore stopped by the Today show on Friday to promote the show, where she opened up on how the role "came in the middle of the moment in my life where I had let myself go due to personal circumstances," and playing the flesh-eating Sheila allowed her to "come alive” with her undead character. Check out the video below to hear more.