"Everything's uncomfortable," she admitted. "Everything gets bigger. It's not just your belly, like, I've never seen my thighs so big, and my boobs... they're in the way of everything. It's hard."
Discomfort aside, Longoria admitted that she often does forget that she's even expecting, a sentiment she also recently shared with ET.
"The other day, I was sleeping and the alarm went off, and I was gonna jump out of bed. And I was like, 'What's happening? I can't get up!'" she quipped to Kimmel, adding that she also had another memory lapse recently when she suggested a ski trip to her husband.
"My husband and I were talking about going snow skiing, and I was like, 'Oh my God, we should go next weekend, we're free!'" she said. "And he goes, 'No! You're pregnant!'"
When the parents to be initially found out Longoria was pregnant, the Overboard actress said her husband was concerned about how they were "going to keep this under wraps."
"I was like, 'They've been saying I'm pregnant every month for the last 20 years of my life. It'll be so easy,'" she admitted. "I had a burger, and they're like, 'Eva's pregnant!' And I had a pizza, and they're like, 'Baby bump!' And finally, the tabloids came out, and they're like, 'Eva's gained weight.' And I was like, 'I am pregnant!'"
As for her delivery plans, she shared that both her and Baston's "large families" will be coming out, though she doesn't particularly want them to -- and especially doesn't want anyone in the delivery room.
"I don't want anybody there. I need to absorb this moment by myself," Longoria confessed. "I'll end up taking care of them and cooking for them and making sure they're OK. I don't have time! But they're coming."
After chatting about Longoria's role in the upcoming Overboard remake, out May 3, Kimmel broached the subject of a potential Desperate Housewives reboot.
"It's always coming up in interviews, but no, nobody from ABC has brought it up. We were on for a decade, and we did 24 episodes a year," she said, noting that she and former Desperate Housewives co-star Felicity Huffman are still "very good friends."
For more on Longoria's upcoming bundle of joy, watch the video below.