Phoenix and Zellweger are the reigning Best Actor and Best Actress in a Drama winners, while Awkwafina won Best Actress - Motion Picture Musical/Comedy.
ET has learned that presenters will appear live at The Beverly Hilton in Beverly Hills or Rainbow Room in New York City when the show takes place on Sunday, Feb. 28. Invited presenters have been assured by Globes producers that rigorous COVID-19 protocols will be in place.
Nominees, meanwhile, are expected to appear remotely.
The awards ceremony was pushed back from its typical January date due to the COVID-19 pandemic. Tina Fey and Amy Poehler will host the show from opposite coasts, with Fey at the Rainbow Room and Poehler at the Beverly Hilton. The two former Saturday Night Live stars hosted the ceremony for three straight years, from 2013-2015.