The politically charged sketch kicked off with a White House press conference led by Mike Pence (Beck Bennett), who explained, "We've assembled a brilliant team of the most talented people left in government."
Pence was joined by Ben Carson (Kenan Thompson) for an update on the epidemic, and his best advice was to buy some "Make America Great Again" face masks. However, it'll take a while for them to come in, since they're made in Wuhan, China.
After asking the press not to politicize the virus or people's reactions, Pence took questions from the reporters. The first came from Democratic candidate Mike Bloomberg (SNL alum Fred Armisen), and the entire sketch quickly became another version of the guest-star packed Democratic debate sketches that have become a recurring fixture of the season.
This week, host John Mulaney took on the role of Joe Biden (after the former Vice President was played by Woody Harrelson and Jason Sudekis), and Pence called out the change, asking, "Joe Biden? You look different."
"Yeah, the surgery is starting to settle," Mulaney's Biden shot back, while rocking a South Carolina beauty pageant sash.