Hugh Grant was the first to call out an online hater, reading a tweet that stated, "Watching Hugh Grant and his stutteringly pathetic 'charm' is about as appealing to me as closing my scrotum in a DVD case."
"Are these real or do you make them up to be especially nasty?" Grant asked, looking up from his phone with a crestfallen gaze. For the record, they aren't made up -- the internet really is home to some terrible people.
Kate Hudson found her needlessly mean tweet quite a bit funnier, as she broke into laughter while reading, "Kate Hudson is a dead eyed trash bag that smells like low tide."
While some of the mean tweets were overtly hateful (or, in the case of Norman Reedus, just an offer from one Twitter user to have some very graphic sex), not every hurtful comment was filled with rage.
For Paul Rudd, the insult was simply that he seemed like a nice, normal guy.
"Paul Rudd is the most boring, vanilla dude," the Ant-Man star read off of a phone. "You know he just sits at home with his wife having a bland spaghetti dinner talking about his day."
A lot of the attacks were based solely on the star's physical appearance. For example, Zac Efron read one tweet that asked, "Has Zac Efron ever been in a film where he didn't play a total douche? I've never seen one of his films, I'm just judging by his face."
Even the notoriously mercurial Russell Crowe got in on the fun, and could help but chuckle when he read, "Russell Crowe is delightfully paradoxical in that he is a huge d**k with a small penis."
The new installment also features mean tweets read by Greg Kinnear, Melissa McCarthy, Chris Evans, Jane Lynch, Margot Robbie, Anthony Mackie, Judd Apatow, Olivia Wilde, Ryan Gosling, Wanda Sykles, Bryan Cranston and Kiefer Sutherland.