Don Rickles, Legendary Comedian and Actor, Dies at 90

This video is unavailable because we were unable to load a message from our sponsors.

If you are using ad-blocking software, please disable it and reload the page.

Rest in peace, Don Rickles.

The iconic comedian died of kidney failure on Thursday morning, his rep tells ET. He was 90.

WATCH: Mary Tyler Moore Dies at 80

Throughout his career, Rickles had great success as both an actor and best-selling author. The Emmy winner started his work as a stand-up comedian in the 1950s after being honorably discharged from the U.S. Navy after serving in World War II. Following years of "insult" comedy work, Rickles made his dramatic film debut in 1958's Run Silent, Run Deep, and spent the next several decades working in both film and television.

In 1965, Rickles made his first appearance on The Tonight Show Starring Jimmy Carson, and appeared on the show more than 100 times throughout Carson's reign. Rickles' stage quickly expanded past television, as he performed at the presidential inaugurations of Ronald Reagan and George H.W. Bush with his friend, Frank Sinatra.

Rickles was honored with a star on the Hollywood Walk of Fame in 2000, and in 2008, he won an Emmy for Individual Performance in a Variety or Music Program for Mr. Warmth: The Don Rickles Project. In 2014, Rickles was honored by Spike TV's One Night Only: An All-Star Comedy Tribute to Don Rickles, which featured tributes by Johnny Depp, Martin Scorsese, Robert De Niro, Jon Stewart, David Letterman, Tracy Morgan, Brian Williams, Regis Philbin, Amy Poehler and Tina Fey.

RELATED: Robert Osborne, Turner Classic Movies Host, Dies at 84

At 90 years old, Rickles continued to make appearances on late-night talk shows, including Jimmy Kimmel Live! and The Tonight Show Starring Jimmy Fallon, and made a cameo on Fox's 2015 comedy, Grandfathered.

He is survived by his wife of 52 years, Barbara, as well as his daughter, Mindy Mann, and two grandchildren. Funeral services will be private, though in lieu of flowers, the family suggests that donations be made to the Larry Rickles Endowment Fund at Children's Hospital Los Angeles.

WATCH: Mary Tyler Moore Laid to Rest in Connecticut