Rob Lowe Teases Sean Penn Over El Chapo Interview With a Perfect 'Fast Times at Ridgemont High' Joke

Rob Lowe's got jokes!

The Grinder star couldn't help poking a little fun at his longtime pal Sean Penn on Sunday's Golden Globes red carpet, weighing in on the news that Penn had secretly interviewed Mexican drug lord El Chapo for Rolling Stone.

READ: Stars Share Mixed Reactions to Sean Penn's El Chapo Interview 

"Did Sean catch him?" Lowe asked ET's Nancy O'Dell, throwing it way back to 1982 with a priceless Fast Times at Ridgemont High reference. "To me, it almost seems like Jeff Spicoli trying to cut out the middle man."

Lowe admitted that he hasn't read Penn's interview yet, but he's definitely seen that hilariously awkward handshake picture. "The photo is one of the greatest photos I've ever seen," Lowe laughed.

NEWS: Sean Penn's El Chapo Interview Led to Fugitive's Arrest, Say Mexican Officials 

Before they were famous, Lowe and Penn were classmates at Santa Monica High School, along with Charlie Sheen and Robert Downey Jr.

"Listen, it's a big accomplishment from [a] fellow Santa Monica High [student]," Lowe cracked. "Look, the people who went to Santa Monica High -- we get s**t done. Let's face it. We do! We find drug lords, we get nominated for Golden Globes, we do a lot of stuff."

Lowe is nominated for his very meta role as an actor in The Grinder at this year's ceremony.

"I love that our funny little show has been recognized so early. We're only eight or nine episodes in, so to get this nomination -- it's a tribute to how good the show is," Lowe gushed.

WATCH: Rob Lowe Reveals His Surprising Secret to Staying Young on 'The Grinder' Set 

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