The 58-year-old reality star is exiting the series after nine seasons.
It's the end of a reality TV era.
"It was a very difficult year for me, personally and professionally… The Housewives, it’s just, it’s emotionally too difficult to deal with," she told Us Weekly, who were the first to report the story on Thursday.
The news came one day after Andy Cohen revealed that Vanderpump did not attend the RHOBH season 9 reunion.
Cohen went live on his Instagram during a break while shooting the reunion to reveal that the 58-year-old TV star, who was an original cast member when the show kicked off in 2010, wasn't in attendance.
"There’s major things happening," Cohen hinted on Wednesday. "There’s trouble afoot in Beverly Hills."
For more on the ongoing drama between Vanderpump and her RHOBH co-stars, check out the video below.
'RHOBH': Lisa Vanderpump Says Lie Detector Results Prove Her 'Puppygate' Innocence '1,000 Percent'