ET spoke with the 43-year-old actress at a sneak peek screening of The Morning Show at the Paley Center and she eagerly speculated over which fan favorites may reprise their role in the upcoming film, which will follow the 2001 original and its 2003 sequel.
"It's just a development project right now, so we'll see," Witherspoon cautioned, before calling out some of the movie's fan favorite characters.
"I love Jennifer Coolidge and Luke Wilson and Selma Blair and so there's so many great characters that people love," Witherspoon continued, naming Elle Woods' onscreen BFF Paulette, her husband, Emmett, and frenemy Vivian, respectively. "If we end up doing it, hopefully they end up all being there."
While Legally Blonde 3is a long way from hitting theaters, fans will soon see Witherspoon in her latest project, The Morning Show, which she co-stars in and co-produced with Jennifer Aniston.
"I don't think we're used to seeing two female leads in anything. I don't think we're used to it because I don't think we've had enough of it," she said of the AppleTV+ series, which follows the morning show anchors after their male co-star, Mitch Kessler (Steve Carell), is fired for alleged sexual misconduct.
"Hopefully this is a time and cultural shift that we'll start to see more dynamic relationships between women because they're not adversarial or best friends," she continued. "There's a whole other spectrum of human behavior in there."
Witherspoon also spoke to whether her fictional worlds could cross over with a guest starring role for some of her Big Little Liesco-stars on The Morning Show, stating, "I would love all of them to be on the show."
With all that love for her BLL cast mates, Jimmy Fallon couldn't help but inquire about a potential third season of the HBO series when Witherspoon stopped by The Tonight Showon Tuesday.
"I don't know. I guess it matters if the audience wants it. Do you want it?" Witherspoon asked the audience, who responded with energetic cheers.
As for how she managed to land all of her recent incredible acting roles and producing credits -- including The Morning Show, BLL, Gone Girl, Wild, and more -- Witherspoon told Fallon that it all started after she read an awful script eight years ago.
"I read a really crappy script and it got me so mad... I called my agent and I said, 'I'm not doing this. This is terrible.' It was like the girlfriend and she was dumb and she had no point. And my agent said to me, 'Every woman in town wants this part,'" she recalled. "And I thought, 'If this is the kind of stuff that's in Hollywood, I have to start making my own stuff.'"