The single marks the first time the artists have collaborated together.
The Backstreet Boy dished on auditioning for Ricky Martin & how identity struggles shaped his album, now streaming exclusively on ET.
The singer also dished on his new solo record and having his 10-year-son, James, play a younger version of himself in his new video.
The singers sweetly escorted their gorgeous wives on stage during their final 'Larger Than Life' residency gig in Las Vegas.
The boy band was formed on April 20, 1993.
The boy band also had a special Q&A at the Grammy Museum in Los Angeles on Monday.
ET talked to the group about the new 'Boy Band Con' documentary, which centers on their early manager, late mogul Lou Pearlman.
While 'Property Brothers' star, Drew Scott, was hoping his wife would be serenaded, McLean couldn't resist choosing his cute daughters!
Twain couldn't hide her excitement as she was pulled on stage by McLean at the Backstreet Boys' 'Larger Than Life' residency show.
The boy band and rapper collaborated for a fun new Super Bowl commercial.
The boy band also shares their first impressions of one another.
The boy band will be releasing their tenth studio album on Jan. 25.
The five singers reflect on being together for 25 years, their ups and downs, and what they call their 'second chance.'
The couple told ET that all they need now is to get the "Don't Go Breaking My Heart" singers to their wedding -- but there'll be endless Backstreet Boys music regardless!